Last Actualized: 23/07/2008
 

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Metallothionein Research

PhD Thesis

Premi Joan Oró

Llegint el llibre de la vida

 
 

Research Articles

Metal-binding features of the mussel M.edulis MT-10-IV recombinant metallothionein: a polyvalent role in Zn, Cu and Cd housekeeping. Journal of Biological Inorganic Chemistry, 13(5):801-12 (2008).Orihuela R, Domènech J, Bofill R, You C, Mackay E, Kägi J, Capdevila M, Atrian S. Download Abstract

Comparative insight into the Zn(II)-, Cd(II)- and Cu(I)-binding features of the protozoan Tetrahymena pyriformis MT1 metallothionein. Biochim. Biophys. Acta, 1784(4):693-704 (2008). Domènech J, Bofill R, Tinti A, Torreggiani A, Atrian S, Capdevila M. Download Abstract

Structural study of the zinc and cadmium complexes of a type 2 plant (Quercus suber) metallothionein: insights by vibrational  spectroscopy.  Biopolymers, 86(3):240-8.  (2007). Domènech, J., Tinti. A., Capdevila, M., Atrian, S.,Torreggiani, A. Download Abstract

The Cd-binding abilities of Quercus suber metallothionein, QsMT: bridging the gap between phytochelatins and metallothioneins.  Journal of Biological Inorganic Chemistry, 12: 867-882. (2007). Domènech, J., Orihuela, R., Mir, G., Molinas, M., Atrian, S., Capdevila, M. Download Abstract

The four members of the Drosophila metallothionein family exhibit distinct yet overlapping roles in heavy metal homeostasis and detoxification. Genes to Cells, 11(6), 647-658 (2006).  Egli D, Domenech J, Selvaraj A, Balamurugan K, Hua H, Capdevila M, Georgiev O, Schaffner W, Atrian S. Download abstract

Functional insight into plant metallothionein domains: physiological metal binding and protein folding. Biochimie, 88(6):583-93 (2006). Domenech J, Mir G, Capdevila M, Molinas M, Atrian S. Download Abstract

Zn- and Cd-Metallothionein Recombinant Species from the most Diverse Phyla May Contain Sulphide (S2-) Ligands.  Angew. Chem. Int. Ed. 44(29):4618-4622. (2005). Capdevila M, Domenech J, Pagani A, Tío L, Villarreal L, Atrian S.Download Abstract

A plant type 2 metallothionein (MT) from cork tissue responds to oxidative stress.  Journal of Experimental Botany, 55(408): 2483–2493 (2004). Mir G, Domenech J., Huguet G, Guo WJ, Goldsbrough P, Atrian S, Molinas M. Download Abstract

MTO: the second member of a Drosophila dual cooper-thionein system. FEBS Letters 533: 72-78 (2003). Domenech J., Palacios O., Villareal L., González-Duarte P., Capdevila M., Atrian S. Download Abstract

 

Research Communications

2008

EUCMOS 2008.XXIX European Congress on Molecular Spectroscopy (Opatija, Croatia,August 31st – September 5th). Raman spectroscopy investigation on  metal-Metallothionein complexes. A. Tinti, J. Domènech, S. Atrian, M. Capdevila, A. Torreggiani

XIV CONVEGNO NAZIONALE DELLA SOCIETÀ ITALIANA PER LE RICERCHE SULLE RADIAZIONI (S.I.R.R.) (Trieste, 24 - 27 giugno 2008). Metallotioneine sottoposte a stress radicalico: alterazione della struttura e induzione di processi di desolforizzazione. A. Torreggiani, J. Domènech, R. Orihuela, C. Ferreri, M. Tamba, S. Atrian, M. Capdevila, C. Chatgilialoglu

2007

XII European Conference on Spectroscopy of Biological Molecules (Paris, 1-6 September 2007-accepted). Structural Lesions of Sulfur-containing Proteins caused by Radical Stress: Assessment and Tandem Radical Potential, A.Torreggiani, J. Domènech, C. Ferreri, C. Chatgilialoglu.

Reunión Científica de Bioinorgánica. (Santiago de Compostela, Spain, 2007). Metalotioneínas de planta: ¿el eslabón perdido entre fitoquelatinas y metalotioneínas? R. Orihuela, J. Domènech, G. Mir, M. Molinas, S. Atrian, M. Capdevila.


XX Congresso GNSR (Catania, Italy, 25-29 Giugno 2007). Effect of metal binding (Zn+2 or Cd+2) on the secondary structure and metal clusters of in vivo-synthesized plant QsMT metallothionein. A. Tinti, J. Domènech, M. Capdevila, C. Fagnano, S. Atrian, A. Torreggiani..

XX Congresso GNSR (Catania, Italy, 25-29 Giugno 2007). Sulfur-containing proteins under radical stress: damage selectivity and tandem radical potential. A. Torreggiani, J. Domènech, C. Ferreri, C. Chatgilialoglu.

2006

8th European Biological Chemistry Conference EUROBIC 8 (Aveiro, Portugal, 2006). A further step to unveil Metallothionein (MT) functionality:Which is the role of the sulfide ligands of the metal-MT complexes? Capdevila M, Domènech J, Pagani A,Tío L,Villarreal L,Atrian S.

8th European Biological Chemistry Conference EUROBIC 8 (Aveiro, Portugal, 2006). Further insight into a Mytilus edulis metallothionein. Orihuela R, Domenech J, Capdevila M, Atrian S, Bofill R.

9th International Symposium on Applied Bioinorganic Chemistry (ISABC)(Napoli, Italy, 2006). The Cd-binding abilities of Quercus suber metallothionein, QsMT: bridging the gap between phytochelatins and metallothioneins. Atrian, S., Orihuela, R., Domenech, J., Mir, G., Molinas, M., Capdevila, M.

XIII Convegno Nazionale della Società Italiana per le Ricerche sulle Radiazioni (SIRR 2006) (Bologna, Italy, 2006). Danno radicalico di proteine contenenti residui solforati e conseguente alterazione delle membrane lipidiche. Torreggiani, A., Manco, I., Domenech, J., Tamba, M., Ferreri, C., Chatgilialoglu, C.

2005

Metallic Network Symposia(Barcelona, SPAIN, VI-2005). Metal binding abilities of the protozoan Tetrahymena tpMT1, a metallothionein with Cys triplets. Domènech, J. , Bofill, R., Atrian, S., Capdevila, M.Download Abstract.

4th Scientific meeting on Bioinorganics (p40, Calella, SPAIN, IV-2005). Study of the coordinative abilities of the protozoan Metallothionein tpMT1 from Tetrahymena pyriformis. Bofill R, Domenech J, Atrian S, Capdevila M.

Cell Biology of Metals GORDON Conference (Bates College, Lewinston, ME., USA,VII-2005). The presence of sulphide ligands in recombinant ZnII- and CdII-Metallothionein species suggests new capabilities for these metal binding proteins. Capdevila, M., Domènech, J. Pagani, A., Tío, L., Villarreal, L., Atrian, S

Fifth International Conference on Metallothionein (Beiging, China,2005). A further step to unveil Metallothionein (MT) functionality:Which is the role of the sulfide ligands of the metal-MT complexes?  Capdevila, M., Domènech, J. Pagani, A., Tío, L., Villarreal, L., Atrian, S

2004

XII Seminari Conjunt de Biologia Molecular i Biologia del Desenvolupament. Societat Catalana de Biologia (Barcelona, SPAIN, VI-2004). Terminal Histidine determines the coordinative behaviour of CeMTII C.elegans metallothionein. Domènech, J., Capdevila, M., Atrian, S.

II RNEM. 2th National Meeting on Mass Spectrometry(Barcelona, Spain, 2004).  ESI-MS-mediated identification of in vivo-formed metallothionein dimers. Domènech, J., Mir, G., Molinas, M., Capdevila, M., Atrian, S.  Download Abstract. (in spanish)

2003

7th International Congress of Plant Molecular Biology (Barcelona, SPAIN, VI-2003). Isolation and characterization of a metallothionein cDNA found in Quercus suber phellem (cork). Mir, G., Domènech, J., Molinas, M., Atrian, S., Huguet,G.

Research Programs in Horticulture and Landscape Architecture (West Lafayette, USA, 2003). Isolation of a metallothionein cDNA found in Quercus suber phellem (cork). Mir, G., Domènech, J., Molinas, M., Atrian, S., Huguet, G.

17Èmes rencontres franco-espagnoles (St. Laurent Salanque, FRANCE, XI-2003). Metal binding proteins from a highly stressed tissue. Mir, G.,  Domènech, J., Molinas, M., Atrian, S.


2000-2002

41st Annual Drosophila Research Conference (Pittsburgh, USA, III-2000). Molecular and genetic characterization of Dclk1, a Drosophila homologue of the nematode aging gene clk1. Tricoire, H., Girardot, F., Monnier, V., Lommersee, P., Domènech, J. Download abstract.

6th FIGIPS Meeting in Inorganic Chemistry (Barcelona, SPAIN, VII-2001). Characterization of the Drosophila MTO Metallothionein. Atrian, S., Capdevila, M., Domènech, J., González-Duarte, P., Palacios, O., Villareal, L. Download Abstract

X Seminari Conjunt de Biologia Molecular i Biologia del Desenvolupament. Societat Catalana de Biologia (Barcelona, SPAIN, VI-2002). Characterization of the cordinative behaviour and study of the primary structure of Drosophila melanogaster MTO. Domènech, J., Atrian, S., Palacios, O.,Villareal, L., Capdevila, M., González-Duarte, P.

 

Books or Book Chapters

Research progress on Metallothioneins: insights into structure, metal binding properties and molecular function by spectroscopic investigations. In: Biopolymer Research Trends (2008). Domènech, J., Tinti, A., Torreggiani, A.Download Abstract

Study of the structure-function relationship in metallothioneins of Invertebrates, Plants and Protozoa. PhD thesis. (2008). Departament de Genètica, Universitat de Barcelona. Domènech J. Download Abstract

 

Science Divulgation Articles

Carta d'un caçador de metalls. Premi Joan Oró de Divulgació Científica 2007. Revista Ictíneus 11,6-7 (2008). Disponible a la web de l'Associació Catalana de Comunicació Científica. Download Article.

"La Herencia Humana", Capítol de llibre per l ’Enciclopèdia Infantil Planeta (2006). J.Domènech.

Suplement d'actualització de Zoologia de la Gran Enciclopèdia Catalana (2006). ISBN: 84-412-1401-8. J.Domènech.

Suplement d'actualització d'Ecologia de la Gran Enciclopèdia Catalana (2006). ISBN:  84-412-1406-9. J.Domènech.

Què és el sexe?. Revista Eureka (2006). J.Domènech, C.Gasset, A.Pérez, H.Ruiz. Download Article  

La Sang, font de vida. Revista Eureka (2006). J.Domènech,  C. Gasset i A. Pérez. Download Article

Crear vida en el Laboratori. Revista Eureka (2006). J.Domènech,  C. Gasset i X. Escuté. Download Article

Cercant els nostres orígens. Revista Eureka (2006). J.Domènech,  C. Gasset i X.Escuté. Download Article

 

Digital Contents

Llegint el llibre de la vida. Web divulgativa, Museu Virtual Interactiu sobre l'ADN i la genètica.

 

   
           
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